Before you receive Venofer, tell your doctor if you have low blood pressure, hepatitis, or if you have received many blood transfusions in the past. Procedure Details Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. }|54U|O~?|_v;f\o^(W+/-|^)O65_)rd
sm }[x[)y.z Wz?9_jV0ub,`g`s?oXOSp/Kgw$b!Vb$;IvBVR9n|\0ln=;/=,mgw@do,[";/8nJL{n}Bb-|^6[~>a_1H'^M:^vv=iM+x|+Y Laboratory tests (such as complete blood count, ferritin, transferrin, total iron binding capacity-TIBC) should be performed periodically to monitor your progress or check for side effects. WARNINGS/CAUTIONS: Serious hypersensitivity reactions, including anaphylactic-type reactions (itching, hives, swelling, wheezing, difficulty breathing, fainting and/or other allergy symptoms), some of which have been life threatening and fatal, have happened in patients receiving Venofer. To make sure Venofer injection is safe for you, tell your doctor if you have: hemochromatosis or iron overload (the buildup of excess iron). In this study, compared with their level before treatment: Injectafer isnt currently approved for use in children. Venofer also comes as a liquid thats given by either IV infusion or a slow IV injection. reese0809 1 yr. ago. Consult your doctor before breast-feeding. Venofer (iron sucrose) injection, USP is an intravenous (IV) form of iron, which is a key ingredient for making new red blood cells. Iron is an essential nutrient needed to maintain energy levels and keep you healthy. This is why family members often have the same issues with drugs as others in theirfamily. %PDF-1.3 Weight changes may be due to symptoms of anemia improving. Weight influences how fast medication breaks down in the body, so it also affects how longside effectswill last. You may report side effects to FDA at 1-800-FDA-1088. Notify your healthcare provider if you are pregnant, or planning to get pregnant or breastfeeding. People who weigh less than 110 lb (about 50 kg) will receive two separate Injectafer doses of 15 mg/kg of body weight. This includes your doctors, nurses, pharmacists, and dentists. Keep in mind that there may be additional costs related to getting your doses of the drug at a medical facility. With slow IV injection, the drug is given as a single, slow injection into your vein. Call your doctor for medical advice about side effects. Renal elimination is negligible. Its not known for sure how often this condition occurred during clinical trials, or if it occurred at all during the trials. Its responsible for carrying oxygen throughout your body. Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when Venofer is injected. The actual price youll pay for either drug depends on your insurance plan, your location, and the pharmacy you use. Injectafer is approved to treat iron deficiency anemia (IDA). Tell your doctor if you are taking iron supplements or other iron-based oral medications. Injectafer isnt a medication that youll take regularly on a schedule. Side effects: DayQuil can cause side effects such as drowsiness, dizziness, nausea, vomiting, and stomach upset. If this happens, you may need to get another treatment course of Injectafer, if your doctor recommends it for you. This medication is given by injection into a vein as directed by your doctor. Many people using this medication do not have serious side effects.Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. For reasons we dont fully understand, some peoples immune system gets over-activated when the drug enters their body. Speak to yourhealth careprofessional for medical advice on if the dosage should bereduced. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. After receiving IV iron therapy, you will be monitored for 30 minutes to make sure you do not have an allergic reaction or a drop in blood pressure. Keep in mind that the risk of certain pregnancy-related problems can be increased if iron deficiency anemia (IDA) is left untreated. The actual price youll pay depends on your insurance plan and any copays, your location, and the pharmacy you use. Venofer injection contains iron sucrose, a form of the mineral iron. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. <> Theseside effectsmay last as long as they are undercancer treatment. Knowing how longside effectslast can help with the decision on whether to use a particulardrug. experience severe side effects, please seek medical attention right away and notify the ordering physician. Drug class: Iron products. Before using iron sucrose, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Once you have waited for 30 minutes after the injection, you may go home, providing you are feeling well. Hes an expert in genetic testing, genetic analysis, andprecision medicine. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Venofer, or with both drugs (when taken individually). It belongs to a class of medications called iron replacement products. The rest of the people switched from taking iron by mouth to taking an iron product other than Injectafer thats given by IV. Generics tend to cost less than brand-name drugs. The following information describes dosages that are commonly used or recommended. endobj Injectafer is available only as a brand-name medication. This could happen because Injectafer helps increase their hemoglobin levels, but it doesnt address the underlying cause of their anemia. Feraheme also comes as a liquid thats given by IV infusion. Pain, swelling, or redness at the injection site may occur. Dizziness. During pregnancy, this medication should be used only when clearly needed. This allows them to manage any side effects that you may have following your dose. This is only a brief summary of general information about this medicine. Most mild side effects of Injectafer typically go away within about 30 minutes of receiving your dose of the drug. If you have questions about drinking alcohol while youre taking Injectafer, talk with your doctor. On the other hand, some people may have a poor appetite that goes away when their anemia is treated. In one study, treatment with Injectafer was compared with that of iron thats taken by mouth. What is the latest research on the form of cancer Jimmy Carter has? After getting each dose of Injectafer, your healthcare professional will monitor you for at least 30 minutes. Follow all instructions closely. Now I've just got mild nausea and have felt faint/dizzy a few times which is rare for me. I can't take oral supplements because they cause horrible debilitating Constipation. This website is intended for use by US patients. Venofer is not for treating other forms of anemia not caused by iron deficiency. This is a sudden response affecting the entire body, which sometimes happens to people who are allergic to peanuts or beestings. Before approving coverage for Injectafer, your insurance company may require you to get prior authorization. People with IDA have low blood levels of hemoglobin. Taking a higher dose than needed can often lead to adverse effects. Total cumulative Venofer dose = number of 100mg ampoules for Hb increase. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. For instance, someone with lowblood pressuremay receive a medication to prevent migraines that lowersblood pressure, this may causeseriousside effects. Keep all regular medical and laboratory appointments. Patients with celiac disease (gluten intolerance). In clinical studies, Injectafer was effective in treating IDA in adults who either didnt improve with or had side effects from taking iron by mouth. (A generic drug is an exact copy of the active drug in a brand-name medication.). Together, you and your doctor can develop a treatment plan thats best for you. Most people do not know how long theirside effectswill last until they go through them. To help make sure that you dont miss appointments for your Injectafer doses, try setting an appointment reminder on your phone. If you have any of these health problems: Too much iron in your body or anemia from a cause other than low iron. Not all possible drug interactions are listed here. If you come into contact with Red Tide, it can cause respiratory irritation, coughing, and sneezing. Symptoms include shock, dangerously low blood pressure, loss of consciousness, and/or collapse. However, since peoples bodies react so differently to drugs, they often have to change their stance on certaindrugs. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Innovators Monograph Since side effects are similar between 150 mg and 300 mg, a larger dose may increase severity or frequency of side effects. Dr. Colby is alsothe Founder of Sequencing.com and the authorofOutsmart Your Genes. endobj Erectile dysfunction, anothercommonside effect, can affect life significantly leading to depression and failedrelationships. These nutrients include iron, vitamin B12, and folate. No, you wont need to take iron pills while youre using Injectafer. Find out what health conditions may be a health risk when taken with Venofer Vial In the second group, some people switched from taking iron by mouth to taking Injectafer. Other drugs may interact with iron sucrose, including prescription and over-the-counter medicines, vitamins, and herbal products. No, you most likely wont take Injectafer long term. If you are allergic to Venofer; any part of this medicine; or any other drugs, foods, or substances. Symptoms of overdosage include drowsiness, mental confusion, dizziness, diarrhea and vomiting etc. In clinical trials,. For people weighing less than 50 kg, administer Injectafer in two doses of 15 mg/kg of body weight, at least 7 days apart. Pain, swelling, or redness at the injection site may occur. Iron infusions are given directly into a vein. cough. This is why the FDA hasa programcalledMedWatchthat encourages Americans to report adversereactions. Hemoglobin is a protein thats found inside your red blood cells. Drug interactions: DayQuil can interact with other medications, including prescription drugs, over-the-counter medications, and herbal supplements. If you are breastfeeding, tell your doctor if you notice diarrhea or constipation in the nursing baby. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. This hormone is made by your kidneys. I got Venofer twice in the last few years and now my iron deficiency is worse than ever, first time my hemoglobin is down to 11,2. Talk with your doctor. Administer Venofer in 3 divided doses, given by slow intravenous infusion, within a 28 day period: 2 infusions each of 300 mg over 1.5 hours 14 days apart followed by one 400 mg infusion over 2.5 hours 14 days later. These are not all of the side effects that may occur. For more information about Injectafers approved uses, see the section Injectafer uses below. You may report side effects to Health Canada at 1-866-234-2345. Its FDA-approved to treat iron deficiency anemia (IDA) in adults. For more information and to find out if youre eligible for support, call 877-4-IV-IRON (877-448-4766) or visit the program website. Iron infusion side effects vary depending on which form is being used. Typical Injectafer doses for iron deficiency anemia (IDA) depends on your body weight. intense abdominal pain. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: These are not all of the side effects that may occur. Last updated August 20, 2020. Maximum concentrations of Injectafer are achieved within 15 minutes to 1.21 hours following administration. Iron infusion benefits. Some people may also experience skin irritation from the adhesive tape and other medical equipment used during the procedure. 5 0 obj Brand-name medications usually cost more than generics. If you have questions about side effects, call your doctor. Throw away unused or expired drugs. If you need to store Venofer at home, talk with your doctor, nurse, or pharmacist about how to store it. With CKD, your kidneys dont function properly, which can lead to your body having problems using iron. Serious side effects, which are explained in more detail below in Side effect details, include: You may wonder how often certain side effects occur with this drug. Instead, youll start by receiving just one treatment course of Injectafer. Last reviewed . stream monitor along with your hemoglobin and red blood cell count: The Venofer patient brochure provides information and support for CKD patients (2 years and older) with IDA. Fortunately, knowing how longside effectslast can help those suffering know what to donext. Your doctor will do laboratory tests to monitor your response. Common MRI side effects include dizziness, anxiety, headache, nausea, hearing loud noises, and feeling chilled or hot in the MRI scanner. But for other people, doing so could lead to having too much iron in their body. Mental healthdisorders like depression may requireantidepressantsto treat. Venofer can be given as a maximum of 200mg not more than 3 times per week; doses must be 24 hours apart. Some may be a better fit for you than others. Its responsible for carrying oxygen throughout your body. For more information on the possible side effects of Injectafer, talk with your doctor or pharmacist. With this condition, you also have a low hemoglobin level. These effects typically last between 7 and 11 hours. There may be risks to the mother and fetus associated with untreated IDA in pregnancy. The insurance company will review the prior authorization request and decide if the drug will be covered. Your doctor will recommend whether you should stop taking your multivitamin or any other supplements. Evenbirth controlcan lead to severeside effectslike bloodclots. They can recommend if this is safe for you to do. These side effects can range from being mild to severe. This means you would get two Injectafer doses of 720 mg each. You should not receive Venofer if you have ever had an allergic reaction to an iron injection, or if you have iron overload (the buildup of excess iron) or hemochromatosis. However, consuming large amounts of alcohol can actually cause anemia in some people. Venofer (iron sucrose) can also be mixed in a saline solution and given through an IV over a longer time. This product may contain inactive ingredients, which can cause allergic reactions or other problems. The infusion concentration should not be less than 2 mg of Injectafer per mL of solution. Venofer is manufactured under license from Vifor (International) Inc., Switzerland. MNT is the registered trade mark of Healthline Media. In fact, Injectafer is meant for some people whose anemia didnt improve with iron pills or for people who had side effects from iron pills. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. 2023 Medicine.com All rights reserved. Other drugs are available that can treat iron deficiency anemia (IDA). To help make sure that you dont miss an appointment for your Injectafer dose, try setting an appointment reminder on your phone. Learn about the causes, symptoms, diagnosis, and treatment of this. But if they become more severe or dont go away, talk with your doctor or pharmacist. The Food and Drug Administration (FDA) approves prescription drugs such as Injectafer to treat certain conditions. Follow your doctor's directions carefully. Its possible to get rid of or reduce the severity ofside effects. I actually was constipated after my 3rd but didn't think anything of it. Blood tests may be needed to check for unwanted effects. Iron sucrose injection has a molecular weight of approximately 34,000 - 60,000 daltons and a proposed structural formula: Treatment with Venofer injections can make it harder for your body to absorb iron medications you take by mouth. Learn about uses, cost, how it works, and more. Then the study was split into the following two groups, which are discussed below. The Role of Genetics in Multifactorial Disorders, The Power of DNA Testing and Predictive Medicine, A Guide to Genome Explorer (Free Version), Whole Genome Sequencing in As Little As Three Weeks, What Diseases Can Be Detected Through Genetic Testing, Breast Cancer Genetic Testing: Pros and Cons, At Home Genetic Testing for Breast Cancer, DNA Tests for Breast Cancer Genetic Testing, What to Do When Medicines Have Side Effects, Blood Type and COVID: Infection Risk and Severity, Where Can I Get My Blood Type Checked for Free, How to Find Biological Father Through DNA. wAd**CgI%"nn{Oa[q{r5 muscle pain. Answer by DrLact: About Venofer usage in lactation. This is not a complete list of side effects and others may occur. But in some people, Injectafer can cause symptoms of hypophosphatemia to occur. There may be drug take-back programs in your area. Side effects from HRT depend on a number of factors: Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. I was surprised too but the Dr said it definitely sounds like a reaction. Injectafer comes as a liquid solution inside vials. But you likely wont feel the drug working inside of you. Diarrhea is a common side effect of most iron replacement products, which is the group of drugs that Injectafer belongs to. Venofer treatment may be repeated if iron deficiency reoccurs. Your doctor will determine the best dosage to fit your needs. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Without enough hemoglobin, the right amount of oxygen may not reach certain parts of your body. Below are examples of these side effects. Injectafer should be stored between 68F to 77F (20C to 25C). However, be sure to take the dosage your doctor prescribes for you. Keep out of reach of children. Dizziness. With IDA, you have low hemoglobin levels. If needed, theyll recommend treatment, including certain medications. Low iron saturation, or iron deficiency, has various possible causes. Severeside effectsmay end up causing a lot of disruption in a persons life. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, Treating Opioid Use Disorder With Medications, Constipated? You may also need to monitor your blood pressure at home. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Click below for effective ways to alleviate the discomfort felt fromside effects and learn how to get a free Medication and Drug Reaction DNAReport. But keep in mind that in this study, delayed allergic reaction only occurred in one person. Learn how to store and discard medical supplies safely. But the length of time that this may take varies from person to person. In the first group, some people continued taking iron by mouth, while other people took Injectafer. Common side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting; diarrhea; treatment schedule in further detail. Some products that may interact with this drug include: vitamin products, other iron-containing products. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. fever. Its given by either intravenous (IV) infusion or slow IV injection. Check with your pharmacist if you have questions about the best way to throw out drugs. (See also Notes section.). We comply with the HONcode standard for trustworthy health information. This treatment course is split into two doses of the drug, which are given at least 7 days apart. 4 0 obj You may report side effects to the FDA at 1-800-332-1088. You may wonder how Injectafer compares with other medications that are prescribed for similar uses. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. Is the ketogenic diet right for autoimmune conditions? Only 10 mg may be excreted by the body the next time it goes through the liver, and possibly only 5 mg the nextpass. reactions at the site of the injection. fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes discharge or excessive tearing Do not flush down a toilet or pour down a drain unless you are told to do so. Depending on your anemia symptoms, your weight changes may be different than those described here. For instance, there are some experts who believe there are long-lastingside effectsfromCOVIDthat were not aware of just yet. Usually, but not always, the bigger a person is the slower it takes for drugs to break down and leave the body. signs of inflammation in the lining of your stomach --pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, fever. So the goal of anemia treatment is to increase your hemoglobin level back to a value thats within a normal range. (IV iron is absorbed by the body more rapidly than oral iron.) Notify your healthcare provider of all medical conditions and any medications, including supplements you are taking. <> Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. If you are using this medication at home, learn all preparation and usage instructions from your health care professional. Serious side effects from Injectafer arent common, but they can occur. % What Is the Cost of Whole Genome Sequencing (WGS)? taste impairment. Low blood pressure. It can also cause skin irritation and redness. Injectafer and Venofer are both brand-name drugs. Properly discard this product when it is expired or no longer needed. For more information about taking Injectafer during pregnancy, see the section Injectafer and pregnancy above. Injectafer contains the active drug ferric carboxymaltose, while Venofer contains the active drug iron sucrose. And this type of reaction is possible even if you didnt have a reaction to your first dose of the drug. Consult the product instructions and your pharmacist for storage details. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Venofer only for the indication prescribed. chest pain. However, there has been a report of delayed allergic reaction in someone receiving a second dose of Injectafer. Any long-term side effects/dangers from iron infusions? Cancer patients who have anemia and are taking an ESA. You will be watched closely for at least 30 minutes to make sure you do not have an allergic reaction. The recommended dosing guidelines of Injectafer for treating IDA are based on patient weight, as follows: Injectafer contains ferric carboxymaltose, which is a polymer that releases iron into the body. In the studies, peoples hemoglobin level was measured to check for improvement in their anemia. As with all medications, the cost of Injectafer can vary. Dr. Colby holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford Universitys Graduate School of Business, and a degree in Genetics with Honors from the University of Michigan. In the study, peoples hemoglobin level was measured to check for improvement in their anemia. Allergic reactions are most likely to occur within 30 minutes of receiving Venofer. Examples of thisinclude: Not allside effectslast forever. What is Venofer? While this may seem like it would be out of a persons body quickly, the rate of it being broken down is much slower afterward. An LSD comedown is when the mental and hallucinatory effects have worn . If youre concerned about weight changes while youre taking Injectafer, talk with your doctor. One study of just under 5000 HRT users found that 43% were affected. These lists dont include all possible side effects. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. Injectafer isnt available in a generic form. Health careproviderscan provide information on how longside effectslast by checking amedication guide. Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. In stock alternatives of Venofer (based on Iron Sucrose ) Orofer S 200 Injection 1 Injection in 1 Packet 540 569 5% off. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Possibleside effectsareweight gainand suicidal thoughts. Injectafer comes as a liquid thats given by either intravenous (IV) infusion or slow IV injection. Injectafer can cause mild or serious side effects. If you do breastfeed while youre taking Injectafer, the drugs manufacturer recommends that you monitor your child for side effects of the drug. For people with certain medical implants, such as pacemakers, an MRI may pose an . Learn more about the types of tests and treatment. Allergic reactions typically occur the first time your body is exposed to a drug. Very bad and sometimes deadly allergic side effects have rarely happened. XAO$$d|0tX1`Q$Il#FBm}{#h!/;[bOvvg7 ?tMl7/+wya^,~PA}6&Ftb19OeJ6-a3acKjcpkeGq+7/nO AJJ:Okyfp;xw|]McmK?9"t0m%. TheNational Instituteof Health (NIH) and the U.S. Food andDrug Administration(FDA) monitor theside effectsof new and approved medications to ensure safety. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. Some people only need one treatment course of Injectafer. They have been a god send. If you need financial support to pay for Injectafer, or if you need help understanding your insurance coverage, help is available. On day three I had a headache and felt heavy/exhausted, which lasted a few days. "The most common side effects to COVID vaccines include pain at the injection site, fevers, chills, nausea, headaches, tiredness, and painful or swollen lymph nodes in the arm where the vaccine. If your symptoms or health problems do not get better or if they become worse, call your doctor. Injectafer infusions are given over a period of at least 15 minutes. Its important to note that youll get Injectafer doses from a doctor or healthcare professional in a medical facility. However, to be safe, tell your doctor or pharmacist about all prescription, over-the-counter, and other drugs you take before taking Injectafer. Injectafer can be exposed to temperatures between 59F to 86F (15C to 30F) for a short period of time. If either is present, do not use the liquid. Additional studies are ongoing to see if Injectafer is a safe and effective treatment option for these conditions.
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